Outcome of overactive bladder in children
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Published on: August 28, 2020
Stanley Hellerstein1, Amy Ajans Zguta
1The University of Missouri School of Medicine at Kansas City, Missouri, The Children's Mercy Hospital, Kansas City, Missouri 64108, USA.
Insights
Overactive bladder in children often resolves with behavioral changes and medication. Most children experienced symptom improvement or complete recovery after a 3-year follow-up.
Area of Science:
- Pediatric Urology
- Clinical Medicine
Background:
- Overactive bladder (OAB) is a common condition in children.
- Effective management strategies are crucial for improving quality of life.
Purpose of the Study:
- To evaluate the long-term outcomes of OAB management in children.
- To assess the efficacy of behavioral modification and anticholinergic medication.
Main Methods:
- A cohort of 144 children diagnosed with OAB was followed for an average of 3.15 years.
- Initial treatment involved behavioral modification (fluid intake, timed voiding, constipation treatment).
- Anticholinergic medication was administered to non-responders.
Main Results:
- 68 children (47.2%) recovered completely from OAB symptoms.
- 61 children (42.4%) showed decreased symptoms.
- 15 children (10.4%) had persistent OAB symptoms.
- Children with posturing had a higher risk of urinary tract infections.
Conclusions:
- Behavioral modification and anticholinergic medication are effective in managing pediatric overactive bladder.
- A significant majority of children achieve symptom resolution or improvement.
- Posturing may indicate a higher risk for complications like UTIs.
Abstract:
One hundred forty-four children with a clinical diagnosis of overactive bladder were observed for a mean of 3.15 +/- 1.92 years. Initial management consisted of a behavioral modification program that included increased fluid intake, a timed voiding schedule and, if applicable, treatment of constipation. Those who failed to improve with the preceding intervention within 10 days to 2 weeks received an anticholinergic medication. Follow-up information was obtained by telephone. Caretakers and/or patients were asked a standard set of questions. The outcome with respect to urinary urgency, urinary frequency, daytime incontinence, posturing and urinary tract infections was recorded. After an average follow-up period of 3 years, 68 (47.2%) of the 144 children recovered from all symptoms of overactive bladder and 61 (42.4%) had decreased symptoms. Fifteen of the children, or 10.4%, still had all of the symptoms originally associated with overactive bladder. Children who had posturing as one of their symptoms had a significantly increased risk of urinary tract infection.
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