Related Experiment Video
Updated: Sep 20, 2026

Evaluation of Host-Pathogen Responses and Vaccine Efficacy in Mice
Published on: February 22, 2019
The pertussis vaccine controversy in Great Britain, 1974-1986
1Center for the Study of Medical Ethics and Humanities, Duke University, Box 3040 DUMC, Durham, NC, USA. baker009@mc.duke.edu
Abstract:
This historical essay analyzes the role played by Great Britain in the pertussis vaccine controversy of the 1970s and 1980s. Public backlash against this vaccine not only took place earlier in Britain than the United States, but also was so widespread that a series of whooping cough epidemics soon followed. As with the more recent dispute involving measles-mumps-rubella (MMR) vaccine and autism, the United Kingdom played a primary role in defining, promoting, and ultimately exporting this controversy. This essay seeks to explain this phenomenon by situating it in Britain's long history of suspicion regarding vaccines evident among both the public and the medical profession, a theme dating back to the compulsory vaccination laws of the 19th century. It argues that anti-vaccinationism, far from being simply a new development related to the public's lack of awareness of childhood vaccine-preventable illness, actually represents a revival of a much older movement.
Related Concept Videos
Smallpox
Vaccinations
Poliomyelitis
Microorganisms in Medicine and Therapeutics
PPE Use in Healthcare Settings II: Doffing
History of Microbiology

