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Recurrent mesectodermal leiomyoma of the ciliary body: a case report
Seong Hwan Park1, Ji-Hye Lee, Yang Seok Chae
1Department of Pathology, College of Medicine, Korea University, Seoul, Korea.
Journal of Korean Medical Science
|August 19, 2003
Summary
Recurrent ciliary body leiomyoma, a rare tumor, was diagnosed in a young woman. Immunohistochemistry and electron microscopy confirmed smooth muscle differentiation, aiding diagnosis and differentiation from other orbital tumors.
Area of Science:
- Ophthalmology
- Pathology
- Oncology
Background:
- Ciliary body tumors are rare, with mesectodermal leiomyoma being an uncommon subtype.
- Accurate diagnosis is crucial for appropriate management and differentiation from other orbital neoplasms.
Observation:
- A 19-year-old woman presented with decreased visual acuity due to a recurrent ciliary body mass.
- Clinicoradiologic findings suggested recurrence, leading to enucleation under suspicion of malignancy.
Findings:
- Microscopic examination revealed a mesectodermal leiomyoma of the ciliary body.
- Immunohistochemistry showed reactivity for smooth muscle actin and vimentin, excluding other spindle-cell tumors.
- Electron microscopy confirmed myofilaments, indicative of smooth muscle differentiation.
Implications:
- This case highlights the potential for recurrence of ciliary body mesectodermal leiomyoma.
- Distinguishing this rare tumor from amelanotic melanomas and glial tumors is essential.
- Immunohistochemistry and electron microscopy are vital diagnostic tools for identifying smooth muscle differentiation.