Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Elite new anion ligands: polythioamide macrocycles.

Md Alamgir Hossain1, Sung Ok Kang, José M Llinares

  • 1Department of Chemistry, University of Kansas, Lawrence, Kansas 66045, USA.

Inorganic Chemistry
|August 20, 2003
PubMed
Summary

New polythioamide macrocycles show promising anion-binding abilities. Monocyclic compounds exhibit stronger binding for phosphate, sulfate, and fluoride anions compared to bicyclic structures.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The relationship between smartphone usage and sleep quality among university students: a cross-sectional study.

Scientific reports·2026
Same author

A federated learning-benchmarking framework for privacy-preserving UAV intrusion detection using adaptive aggregation algorithms.

Scientific reports·2026
Same author

Residual-aware lightweight deep learning framework for high-fidelity intrusion detection in UAV swarm networks.

Scientific reports·2026
Same author

Prevalence and associated risk factors for social networking addiction among the young generation in Bangladesh.

Discover mental health·2026
Same author

A novel unified lightweight temporal-spatial transformer approach for intrusion detection in drone networks.

Scientific reports·2026
Same author

Using DHIS2 routine data for health system preparedness in resource-limited settings: A Bayesian predictive approach in Bangladesh.

PLOS global public health·2026

Area of Science:

  • Supramolecular Chemistry
  • Organic Synthesis
  • Anion Recognition

Background:

  • Macrocycles are crucial in host-guest chemistry and molecular recognition.
  • Polythioamides offer unique electronic and structural properties compared to polyamides.
  • Developing novel macrocyclic hosts for specific anion binding remains an active research area.

Purpose of the Study:

  • To synthesize novel polythioamide-based macrocycles.
  • To evaluate the anion-binding capabilities of these new macrocyclic compounds.
  • To compare the binding affinities of monocyclic and bicyclic polythioamide systems.

Main Methods:

  • Synthesis of polythioamide monocycles and bicycles via established organic chemistry protocols.
  • Anion-binding studies using techniques such as Nuclear Magnetic Resonance (NMR) titration.

Related Experiment Videos

  • Comparative analysis of binding constants and selectivity for various anions.

    • Main Results:

    • Successful synthesis of prototype polythioamide macrocycles.
    • Demonstrated anion-binding capabilities, particularly for dihydrogen phosphate (H(2)PO(4)(-)), hydrogen sulfate (HSO(4)(-)), and fluoride (F(-)) anions.
    • Monocyclic polythioamides showed enhanced binding affinity compared to their bicyclic counterparts and traditional amide macrocycles.

    Conclusions:

    • Polythioamide macrocycles represent a viable new class of anion receptors.
    • Structural variations (monocyclic vs. bicyclic) significantly influence anion-binding efficiency.
    • These findings open avenues for designing tailored polythioamide hosts for specific anion sensing and sequestration applications.