[Therapy of synchronous multiple primary malignancies]
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Updated: Sep 20, 2026
Competing-Risk Nomogram for Predicting Cancer-Specific Survival in Multiple Primary Colorectal Cancer Patients after Surgery
Published on: September 27, 2024
1Medical State University, Saratov.
Abstract:
The data on 526 patients treated for primary multiple synchronous malignancies were evaluated. The total number of detected tumors was 1,069; concomitant pathology was identified in 377 out of 490 (76.9 +/- 1.9%). Removal of all synchronous tumors was considered radical--and palliative or symptomatic when, whatever the modality, two or at least one tumor was treated. Most of primary multiple synchronous tumors were removed radically (56.4 +/- 2.3%). The best results were obtained when combined therapy was used for early-stage tumors while surgical treatment of advanced cancer was complemented with radiochemotherapy. Radical treatment was contraindicated in 30.3 +/- 3.8% because of concomitant pathology.
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