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A case of adversive seizures induced by hyperventilation
Yasuhiko Kawakami1, Tsunenori Hirayama, Kiyoshi Hashimoto
1Department of Pediatrics, Nippon Medical School Second Hospital, Kawasaki, Kanagawa, Japan. kawakami@nms.ac.jp
Journal of Nippon Medical School = Nippon Ika Daigaku Zasshi
|August 21, 2003
Summary
Hyperventilation can trigger adversive seizures with neck and eye deviation in rare cases. Zonisamide effectively controlled these unique seizure events, highlighting a novel clinical presentation.
Area of Science:
- Neurology
- Epileptology
Background:
- Hyperventilation is a known trigger for absence and complex partial seizures.
- Adversive seizures, characterized by motor symptoms, are less commonly associated with hyperventilation.
Observation:
- A 6-year-old patient experienced adversive seizures with neck rotation and left conjugate eye deviation triggered by hyperventilation.
- Ictal electroencephalogram (EEG) revealed sharp waves in the right frontal, central, and parietal regions during the seizure.
- Brain imaging studies did not show any abnormalities.
Findings:
- This case represents a rare instance of adversive seizures with conjugate deviation induced by hyperventilation.
- The patient's seizures were completely resolved with zonisamide treatment.
- The exact epileptogenesis of these hyperventilation-induced adversive seizures remains unknown.
Implications:
- This case expands the spectrum of seizure types that can be provoked by hyperventilation.
- It underscores the importance of considering hyperventilation as a trigger in patients with unexplained adversive seizures.
- Further research is needed to elucidate the underlying mechanisms of this rare electrophysiological phenomenon.