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Community-acquired febrile urinary tract infection in diabetics could deserve a different management: a case-control
J P Horcajada1, I Moreno, M Velasco
1Infectious Diseases, Institut Clínic Infeccions i Immunologia (ICII), Hospital Clínic Universitari-IDIBAPS, Barcelona, Spain. jhorcaja@clinic.ub.es
Objective:
To investigate if there are relevant differences in clinical, microbiological and outcome characteristics of community-acquired febrile urinary tract infection (UTI) between diabetic and nondiabetic patients.
Design:
A prospectively matched case-control study.
Setting:
An 800-bed tertiary care university-affiliated hospital.
Subjects:
A total of 108 patients (54 diabetic and 54 nondiabetic patients matched by age and gender) admitted between January 1996 and September 1999 with febrile UTI.
Methods:
Clinical, analytical, microbiological and outcome variables were analysed by means of McNemar test (categorical) or Wilcoxon matched pairs signed rank test (continuous).
Results:
Mean age (SD) in both groups was 67.9 (14.4) years. In comparison with controls, diabetic patients were more likely to have fever without localizing symptoms (27% vs. 9%, P
Conclusions:
In diabetic patients, febrile UTIs have clinical and microbiological peculiarities that may have diagnostic and therapeutic implications.