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Beneficial effects of continuous overnight catheter drainage in children with polyuric renal failure

B Montané1, C Abitbol, W Seeherunvong

  • 1Division of Paediatric Nephrology, University of Miami/Jackson Children's Hospital, Miami, Florida 33101, USA.

BJU International
|August 22, 2003
PubMed

Insights

Continuous overnight catheter drainage (COCD) may help preserve kidney function in children with progressive renal disease and bladder issues. This treatment showed a significant slowing of renal decay and reduced infections in most patients.

Area of Science:

  • Pediatric Nephrology
  • Urology
  • Renal Medicine

Background:

  • Children with progressive renal disease often experience dysfunctional bladder syndrome and polyuria.
  • This condition can overwhelm bladder capacity, potentially accelerating kidney function decline.
  • Previous management included surgical bladder augmentation and intermittent catheterization (IC).

Purpose of the Study:

  • To evaluate the beneficial effects of continuous overnight catheter drainage (COCD) in children with progressive renal disease and dysfunctional bladders.
  • To assess COCD's impact on renal function, progression to end-stage renal disease, and urinary tract infections.

Main Methods:

  • Seven pediatric patients with progressive polyuric kidney failure and dysfunctional bladders were treated with COCD.
  • Patients had a history of surgical bladder augmentation and daytime intermittent catheterization (IC).
  • Mean urine output was significantly high, indicating a need for bladder decompression.

Main Results:

  • COCD treatment led to a significant attenuation in the rate of renal function decline (P = 0.02).
  • The predicted time to end-stage renal disease was prolonged by a mean of 12.2 years (P < 0.002).
  • Hospitalizations for febrile urinary tract infections decreased significantly and were eliminated by the second year of COCD.

Conclusions:

  • Continuous overnight catheter drainage (COCD) shows potential for preserving kidney function in select pediatric patients with progressive polyuric renal failure.
  • COCD is a supplementary treatment and does not replace surgical bladder augmentation or daytime intermittent catheterization (IC).
  • This intervention may be a valuable tool in managing complex pediatric renal and bladder conditions.
Abstract

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