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Related Experiment Videos

Behavioral changes associated with deep brain stimulation surgery for Parkinson's disease.

Karen E Anderson1, Jake Mullins

  • 1Division of Movement Disorders, Department of Neurology, University of Maryland School of Medicine, 22 South Greene Street, Room NW49A, Baltimore, MD 21201, USA. kanderson@psych.umaryland.edu

Current Neurology and Neuroscience Reports
|August 22, 2003
PubMed
Summary

Preoperative psychiatric and cognitive evaluation is vital for deep brain stimulation (DBS) surgery candidates. Screening and treating psychiatric disorders can mitigate risks of postoperative behavioral symptoms and cognitive decline.

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Area of Science:

  • Neuroscience
  • Psychiatry
  • Neurosurgery

Background:

  • Preoperative assessment for deep brain stimulation (DBS) surgery must include psychiatric and cognitive evaluations.
  • Active psychiatric disorders require treatment, and past psychiatric history needs screening for potential postoperative psychiatric issues.

Purpose of the Study:

  • To highlight the importance of psychiatric and cognitive evaluations in deep brain stimulation (DBS) surgery candidates.
  • To outline potential psychiatric and cognitive complications following DBS.

Main Methods:

  • Review of current practices and literature regarding preoperative assessment for DBS.
  • Analysis of reported psychiatric and cognitive outcomes after DBS.

Main Results:

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  • A wide spectrum of behavioral symptoms, including depression, psychosis, mania, and impulsivity, can occur post-DBS.
  • Suicidal ideation requires aggressive treatment.
  • Cognitive changes are possible, with limited data on subtle effects, but dementia patients may see accelerated decline.

Conclusions:

  • Comprehensive psychiatric and cognitive screening is essential for DBS candidates.
  • Management of psychiatric disorders pre- and post-DBS is critical.
  • Further research is needed to understand subtle cognitive effects of DBS.