Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Strategies of Self-Presentation I: Strategic Self-Presentation01:12

Strategies of Self-Presentation I: Strategic Self-Presentation

225
Strategic self-presentation refers to individuals' intentional efforts to influence how others perceive them. This process is employed in various social and professional settings, such as job interviews, dating, politics, and legal contexts, where individuals seek to shape impressions to gain social or material advantages. While people generally present themselves in ways that align with their authentic characteristics, external factors, such as cognitive load, can hinder their ability to...
225
Strategies of Self-Presentation II: Self-Verification01:17

Strategies of Self-Presentation II: Self-Verification

196
Self-verification is a fundamental psychological drive wherein individuals seek affirmation of their self-concept from others, striving for consistency between their internal self-view and external perceptions. This drive operates even when the self-concept is negative, influencing interpersonal behavior and feedback preferences in complex and often counterintuitive ways. Unlike the self-enhancement motive, which seeks positive evaluations, self-verification prioritizes coherence and...
196
Persuasion Strategies01:52

Persuasion Strategies

43.5K
Researchers have tested many persuasion strategies, including the foot-in-the door and the door-in-the-face techniques, in a variety of contexts. Ultimately, the principles are effective in selling products and changing people’s attitude, ideas, and behaviors (Cialdini & Goldstein, 2004).
43.5K
Coping Strategies: Problem Focused01:27

Coping Strategies: Problem Focused

522
Coping strategies are methods people use to manage, tolerate, or reduce the effects of stressors. These strategies involve both behavioral and psychological actions to handle stressful situations. One common approach is problem-focused coping, which aims to change or eliminate the source of stress rather than merely addressing its consequences. This method involves taking direct action to resolve the issue causing stress.
For example, consider a student who struggles to understand their...
522
Guidelines and Strategies for Safe Computer Charting01:18

Guidelines and Strategies for Safe Computer Charting

2.7K
The guidelines and strategies provided by the American Nurses Association (ANA) and the Canadian Nurses Association (CNA) offer essential principles for ensuring safe and secure computer charting systems in healthcare settings. Let's break down each recommendation:
Maintain Confidentiality and Security:
2.7K
Coping Strategies: Emotion Focused01:20

Coping Strategies: Emotion Focused

534
Emotion-focused coping refers to a set of strategies aimed at managing the emotional impact of stressors, rather than directly addressing their causes. This approach involves altering one's emotional response to stressful situations to reduce their psychological effects. For example, individuals might talk with a friend or engage in activities like journaling to express their feelings. Such actions can help achieve emotional clarity or release, providing the psychological stability needed...
534

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Association between maternal alcohol consumption during pregnancy and risk of preterm delivery: the Japan Environment and Children's Study.

BJOG : an international journal of obstetrics and gynaecology·2019
Same author

Estimates of hip fracture incidence in Japan using the National Health Insurance Claim Database in 2012-2015.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·2019
Same author

Dehydroxymethylepoxyquinomicin (DHMEQ) can suppress tumour necrosis factor-α production in lipopolysaccharide-injected mice, resulting in rescuing mice from death in vivo.

Clinical and experimental immunology·2011
Same author

Bone marrow-derived stromal cells can express neuronal markers by DHA/GPR40 signaling.

Bioscience trends·2010
Same author

The combination method using magnetic beads and a magnet helps sustain the number of donor BM cells after intra-BM injection, resulting in rapid hematopoietic recovery.

Bone marrow transplantation·2009
Same author

Allogeneic intra-BM-BMT plus adult thymus transplantation from same donor has benefits for long-term survival even after sublethal irradiation or low-dose BM cell injection.

Bone marrow transplantation·2008

Related Experiment Video

Updated: Feb 9, 2026

A Quantitative Assessment of the Phagocytosis of Allogeneic and Xenogeneic Erythrocytes by Rat Macrophages In Vitro
09:01

A Quantitative Assessment of the Phagocytosis of Allogeneic and Xenogeneic Erythrocytes by Rat Macrophages In Vitro

Published on: August 22, 2025

482

New strategies for allogeneic BMT.

S Ikehara1

  • 1First Department of Pathology, Transplantation Center, Regeneration Research Center for Intractable Diseases, Kansai Medical University, Moriguchi City, Osaka, Japan.

Bone Marrow Transplantation
|August 22, 2003
PubMed
Summary
This summary is machine-generated.

New bone marrow transplantation (BMT) methods reduce graft-versus-host disease (GvHD) and improve outcomes. The Perfusion Method minimizes T-cell contamination, while intrabone marrow BMT (IBM-BMT) prevents GvHD and enhances recovery across major histocompatibility complex barriers.

More Related Videos

Transplantation of Tail Skin to Study Allogeneic CD4 T Cell Responses in Mice
06:48

Transplantation of Tail Skin to Study Allogeneic CD4 T Cell Responses in Mice

Published on: July 25, 2014

13.8K
Generation of Multivirus-specific T Cells to Prevent/treat Viral Infections after Allogeneic Hematopoietic Stem Cell Transplant
08:52

Generation of Multivirus-specific T Cells to Prevent/treat Viral Infections after Allogeneic Hematopoietic Stem Cell Transplant

Published on: May 27, 2011

17.8K

Related Experiment Videos

Last Updated: Feb 9, 2026

A Quantitative Assessment of the Phagocytosis of Allogeneic and Xenogeneic Erythrocytes by Rat Macrophages In Vitro
09:01

A Quantitative Assessment of the Phagocytosis of Allogeneic and Xenogeneic Erythrocytes by Rat Macrophages In Vitro

Published on: August 22, 2025

482
Transplantation of Tail Skin to Study Allogeneic CD4 T Cell Responses in Mice
06:48

Transplantation of Tail Skin to Study Allogeneic CD4 T Cell Responses in Mice

Published on: July 25, 2014

13.8K
Generation of Multivirus-specific T Cells to Prevent/treat Viral Infections after Allogeneic Hematopoietic Stem Cell Transplant
08:52

Generation of Multivirus-specific T Cells to Prevent/treat Viral Infections after Allogeneic Hematopoietic Stem Cell Transplant

Published on: May 27, 2011

17.8K

Area of Science:

  • Transplantation immunology
  • Hematopoietic stem cell transplantation

Background:

  • Allogeneic bone marrow transplantation (BMT) success is limited by graft-versus-host disease (GvHD), graft rejection, and poor T-cell recovery, especially across major histocompatibility complex (MHC) barriers.
  • Current methods for collecting bone marrow cells (BMCs) often result in significant T-cell contamination, exacerbating GvHD risks.

Purpose of the Study:

  • To develop novel BMT strategies that overcome GvHD, graft failure, and incomplete immune reconstitution.
  • To establish improved methods for collecting BMCs and administering them for transplantation.

Main Methods:

  • A 'Perfusion Method' was developed for collecting BMCs from cynomolgus monkeys, significantly reducing T-cell contamination compared to the conventional 'Aspiration Method'.
  • An intrabone marrow BMT (IBM-BMT) technique was established using radio-sensitive MRL/lpr mice, involving direct injection of whole BMCs into the bone marrow cavity.

Main Results:

  • The Perfusion Method yielded BMCs with <6% T-cell contamination, versus >20% with the Aspiration Method.
  • Mice treated with IBM-BMT survived over 2 years without autoimmune symptoms, demonstrating no GvHD, no graft failure even with reduced conditioning radiation, rapid hematopoietic recovery, and complete T-cell function restoration across MHC barriers.

Conclusions:

  • The Perfusion Method and IBM-BMT represent significant advancements in allogeneic transplantation.
  • These strategies hold promise for improving allogeneic hematopoietic stem cell transplantation (HSCT) outcomes, particularly for autoimmune diseases.