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[The effect of semen antisperm antibody on human sperm acrosin activity]
Rui-Zhi Liu1, Ying-Li Lu, Zong-Ge Xu
1Department of Cell Biology, School of Basic Medical Sciences, Jilin University, Changchun, Jilin 130021, China.
Objectives:
To study the effect of antisperm antibody(AsAb) on human sperm acrosin activity.
Methods:
AsAb and sperm acrosin activity were measured and analyzed in 3,432 infertile men and 65 fertile volunteers.
Results:
AsAb positive rate was 10.20% in 3,432 case of male infertility, and 9.37% in 2,882 infertile males who received tests of sperm acrosin activity. Acrosin activity of infertility cases were lower than those of fertile cases(P < 0.001). The comparison between AsAb positive group and AsAb negative group infertility cases showed no significant differences of acrosin activity (P > 0.05). Between normal acrosin activity group and abnormal acrosin activity group, there was no significant difference of AsAb positive rate (P > 0.05).
Conclusions:
Antisperm antibody could not affect acrosin activity.