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Evidence for a melanin cell wall component in Pneumocystis carinii
Crystal R Icenhour1, Theodore J Kottom, Andrew H Limper
1Thoracic Diseases Research Unit, Division of Pulmonary, Critical Care and Internal Medicine, Mayo Clinic and Foundation, Rochester, Minnesota 55905, USA.
Infection and Immunity
|August 23, 2003
Abstract:
Fluorescein isothiocyanate-labeled monoclonal antibodies specific for fungal melanin were used in this study to visualize melanin-like components of the Pneumocystis carinii cell wall. A colorimetric enzyme assay confirmed these findings. This is the first report of melanin-like pigments in Pneumocystitis.