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14:56
A Genetic Screen to Isolate Toxoplasma gondii Host-cell Egress Mutants
Published on: February 8, 2012
Host cell fate on Cryptosporidium parvum egress from MDCK cells
David A Elliott1, Douglas P Clark
1Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA.
Infection and Immunity
|August 23, 2003
Abstract:
Cryptosporidium parvum is an intracellular protozoan parasite that causes a severe diarrheal illness of unclear etiology. Also unclear is the fate of the host cell upon parasite egress. We show in an MDCK cell model that the host cell is killed upon parasite egress; this death is necrotic, rather than apoptotic, in nature.
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