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Published on: November 10, 2017
[Changes in fatty acid composition of serum cholesteryl esters in patients with chronic heart failure]
Yan-shu Zhao1, Shui-ping Zhao, Ai-guo Tang
1Department of Cardiology, Department of Clinical Laboratory, Second Xiangya Hospital, Central South University, Changsha 410011, China.
Objective:
To investigate the changes in fatty acid composition of serum cholesteryl esters in patients with chronic heart failure (CHF).
Methods:
The levels of serum TG, TC, HDL, and LDL in 36 patients with CHF and 20 healthy controls were measured and fatty acid cholesteryl esters were determined by high performance liquid chromatography.
Results:
In the patients with CHF, the level of linoleic acid was significantly higher than that in the control group (P < 0.05), but the level of arachidonic acid was significantly lower than that in the control group (P < 0.05). The levels of TC, TG, HDL, and LDL were not significantly different between the two groups.
Conclusion:
Changes in fatty acid composition of serum cholesteryl esters exist in the patients with CHF.
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