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Related Experiment Videos

Pupillometer for clinical applications using dual 256-element linear CCD arrays.

D P Jones1, S J Harris, S R Scicinski

  • 1Department of Medical Electronics, St Bartholomew's Hospital Medical College, London, UK.

Medical & Biological Engineering & Computing
|September 1, 1992
PubMed
Summary

A novel pupillometer utilizes charge-coupled device (CCD) arrays and a microcomputer for accurate human pupil size measurement. This system enables dynamic pupil light reflex response analysis, even in darkness.

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Area of Science:

  • Ophthalmology
  • Biomedical Engineering
  • Medical Instrumentation

Background:

  • Accurate measurement of human pupil size is crucial for various ophthalmic and neurological assessments.
  • Existing pupillometry methods may have limitations in accuracy, speed, or operational conditions (e.g., darkness).

Purpose of the Study:

  • To describe a new, cost-effective pupillometer system for measuring human pupil size and dynamics.
  • To evaluate the accuracy and capabilities of the developed pupillometer.

Main Methods:

  • The system employs two orthogonal 256-element charge-coupled device (CCD) arrays for pupil imaging.
  • A Z80A microcomputer controls data acquisition and analysis, displaying results on a monochrome video monitor.
  • Infrared diodes provide eye illumination, enabling measurements in complete darkness.

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Main Results:

  • The pupillometer achieves an accuracy better than +/- 0.1 mm across a measurement range of 3.2-9.5 mm.
  • Dynamic measurements of the pupil light reflex response are possible with sampling periods as short as 20 ms.
  • The system allows real-time display of pupil position and diameter.

Conclusions:

  • The developed pupillometer offers a precise and versatile tool for both static and dynamic pupil size assessment.
  • Its design, utilizing inexpensive CCD arrays and microcomputer control, presents a cost-effective solution for clinical and research applications.
  • The system's capability for dark measurements and rapid dynamic analysis enhances its utility in studying the pupil light reflex.