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Published on: October 11, 2011
Neonatal abstinence syndrome: strategies for care of the drug-exposed infant
Carol M Greene1, Michael H Goodman
1Division of Neurology, Alfred I. duPont Hospital for Children, Wilmington, Delaware, USA. cgreene@nemours.org
Insights
Neonatal abstinence syndrome (NAS) is a growing concern due to polydrug use. This review covers neonatal effects, clinical care for drug-exposed infants, and current research areas for NAS.
Area of Science:
- Neonatal care
- Pharmacology
- Public Health
Background:
- Neonatal abstinence syndrome (NAS) is a recognized clinical issue with over 30 years of history.
- NAS is increasingly complicated by maternal polydrug use, tobacco, and prescribed psychoactive substances.
- Growing knowledge of NAS, its treatment, and outcomes continues to evolve.
Purpose of the Study:
- To review the neonatal effects of various substances on infants.
- To discuss current clinical care standards for drug-exposed infants, including those with NAS.
- To provide an update on active research areas concerning NAS.
Main Methods:
- Literature review of neonatal effects of substances.
- Synthesis of current clinical care practices for drug-exposed infants.
- Overview of ongoing research in neonatal abstinence syndrome.
Main Results:
- Substance use during pregnancy poses significant risks to newborns.
- Comprehensive care strategies are essential for managing drug-exposed infants.
- Research is advancing understanding and treatment of NAS.
Conclusions:
- NAS remains a significant challenge in neonatal medicine.
- Addressing polydrug use and substance exposure is critical for improving infant outcomes.
- Continued research is vital for refining NAS management and treatment protocols.
Abstract:
Neonatal abstinence syndrome (NAS), a clinical condition that has been recognized for over 30 years, remains a significant clinical issue, although our knowledge of abstinence, its treatment, and outcome continues to grow. The condition is now complicated by polydrug use (which is becoming more prevalent) as well as concomitant use of tobacco, and psychoactive substances that are frequently prescribed to pregnant women. This article reviews the neonatal effects of a variety of substances, discusses the state of the art for clinical care of drug-exposed infants, including NAS patients, and updates the reader on areas of current research.
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