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Related Experiment Videos

Creatine Supplementation Increases Total Body Water Without Altering Fluid Distribution.

Michael E. Powers1, Brent L. Arnold, Arthur L. Weltman

  • 1University of Florida, Gainesville, FL.

Journal of Athletic Training
|August 26, 2003
PubMed
Summary

Oral creatine monohydrate supplementation effectively increased muscle creatine, body mass, and total body water in resistance-trained individuals. Fluid distribution between body compartments remained unchanged by the supplementation protocol.

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Area of Science:

  • Sports Nutrition
  • Exercise Physiology
  • Biochemistry

Background:

  • Creatine (Cr) is a popular supplement for enhancing athletic performance.
  • Understanding its effects on body composition and hydration is crucial for athletes and trainers.

Purpose of the Study:

  • To investigate the impact of oral creatine monohydrate supplementation on muscle creatine levels.
  • To assess changes in body mass, total body water (TBW), extracellular water (ECW), and intracellular water (ICW).

Main Methods:

  • A randomized, placebo-controlled trial involving 32 resistance-trained adults (16 men, 16 women).
  • Creatine supplementation group received 25 g/day for 7 days followed by 5 g/day for 21 days.
  • Muscle creatine concentration, body mass, and body water compartments (TBW, ECW, ICW) were measured before and after supplementation phases.

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Main Results:

  • The creatine group showed significant increases in muscle creatine concentration, body mass, and TBW.
  • The placebo group exhibited a minor but significant increase in TBW only.
  • No significant alterations in the distribution of body fluids (ECW and ICW) were observed in either group.

Conclusions:

  • Oral creatine monohydrate supplementation is effective in elevating muscle creatine stores and increasing body mass and total body water.
  • The supplementation does not appear to alter the distribution of water between intracellular and extracellular compartments.