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Fluid intake and bladder cancer. A case control study.

V Radosavljević¹, S Janković, J Marinković

¹Institute of Preventive Medicine, 11080 Zemun-Belgrade, Serbia. rvladan-Eunet.yu.

|August 26, 2003

Summary

Beverage choices, not total fluid intake, impact bladder cancer risk. Soda, coffee, and spirits may increase risk, while mineral water, skim milk, and yogurt show protective effects.

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Area of Science:

Epidemiology
Nutrition Science
Oncology

Background:

Bladder cancer is a significant public health concern.
Understanding dietary factors, including beverage consumption, is crucial for prevention strategies.

Purpose of the Study:

To investigate the association between total fluid intake, specific beverage types, and bladder cancer risk.
To identify potential risk and protective factors within beverage consumption patterns.

Main Methods:

A hospital-based case-control study was conducted with 130 bladder cancer patients and 130 matched controls.
Beverage intake data was collected using a food frequency questionnaire.
Statistical analysis involved univariate and multivariate logistic regression models.

Main Results:

No significant difference in total daily fluid intake was found between cases and controls.
Consumption of soda (OR=8.32), coffee (OR=1.46), and spirits (OR=1.15) were identified as significant risk factors for bladder cancer.
Mineral water (OR=0.52), skim milk (OR=0.38), yogurt (OR=0.34), and increased urination frequency (OR=0.27) were found to be protective.

Conclusions:

Total fluid intake does not appear to be associated with bladder cancer risk.
Specific beverages like soda, coffee, and spirits may increase bladder cancer risk.
Consumption of mineral water, skim milk, yogurt, and higher urination frequency may offer protection against bladder cancer.

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