[The use of cluster analysis in clinico-neurophysiological study]

Neurophysiological characteristic--an amplitude of P300 auditory evoked potentials (EP) wave registered in 12 and 5 EEG leads--was studied in 22 patients with endogenous psychoses. Using cluster analysis, it was shown that the differences between the EP amplitudes before and after treatment split into clusters thus indicating a fine structure of the data, reflecting an objective changes in the patient's state during the treatment. The results obtained correlated with an evaluation of patient' clinical state by the PANSS, namely with scores on general psychopathological and positive symptoms subscales.