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Related Concept Videos

Gross Anatomy of the Liver01:17

Gross Anatomy of the Liver

The liver, the largest gland within the human body, is a firm and reddish-brown organ. This wedge-shaped structure weighs approximately 1.5 kg and occupies a significant portion of the right hypochondriac and epigastric regions. It extends more to the right of the body's midline than to the left.
Located under the diaphragm, the liver is almost entirely ensconced within the rib cage, providing it with substantial protection. Except for the superior most bare area, the liver's surface is covered...
Liver Histology01:27

Liver Histology

The microscopic anatomy of the liver is a complex and intricate system that comprises numerous structural units known as liver lobules, each of which is comparable in size to a sesame seed. These hexagonal structures consist of plates of liver cells or hepatocytes, which are characterized by their versatility and abundance of cellular apparatus like rough and smooth ER, Golgi apparatus, peroxisomes, and mitochondria.
Hepatocytes perform a variety of essential functions. They secrete...

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Related Experiment Video

Updated: May 21, 2026

Method of Direct Segmental Intra-hepatic Delivery Using a Rat Liver Hilar Clamp Model
09:22

Method of Direct Segmental Intra-hepatic Delivery Using a Rat Liver Hilar Clamp Model

Published on: April 2, 2017

A sewing needle in the liver.

Bernardino Roca1

  • 1Department of Medicine, Hospital General of Castellon, Castellon, Spain. brocav@meditex.es

Southern Medical Journal
|August 27, 2003
PubMed
Summary

An elderly woman with Alzheimer's dementia was diagnosed with giant cell arteritis. An incidental finding of a sewing needle lodged in her liver parenchyma was discovered during imaging.

Area of Science:

  • Geriatrics
  • Internal Medicine
  • Pathology

Background:

  • Alzheimer's dementia can present with various systemic symptoms.
  • Giant cell arteritis (GCA) is a common vasculitis in the elderly.
  • Systemic inflammation markers like erythrocyte sedimentation rate (ESR) are crucial for diagnosis.

Observation:

  • An 85-year-old female patient with Alzheimer's dementia presented with prolonged fever, dyspnea, and pain.
  • Elevated ESR and positive temporal artery biopsy confirmed GCA.
  • Abdominal radiography and CT scan revealed an unexpected finding: a sewing needle within the liver parenchyma.

Findings:

  • The patient's symptoms partially improved with prednisone treatment for GCA.
  • The presence of a foreign body (sewing needle) in the liver parenchyma was an incidental and unusual finding.

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  • The needle's location within the liver parenchyma suggests a potential, though unconfirmed, route of introduction.
  • Implications:

    • This case highlights the importance of comprehensive diagnostic workups, even in patients with known comorbidities like Alzheimer's dementia.
    • Incidental findings on imaging can reveal unexpected pathologies requiring further investigation.
    • The presence of a foreign body within the liver parenchyma raises questions about patient history and potential iatrogenic or accidental causes.