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[Effect of thrombin stimulated blood platelets on plasma fibrinolytic activity]

M Komarnicki1, M Kaźmierczak, D Krupa

  • 1Kliniki Hematologii Instytutu Chorób Wewnetrznych A.M. im. Karola Marcinkowskiego, Poznaniu.

The influence of thrombin stimulated-blood platelets on plasma fibrinolytic activity was evaluated. Thrombin-activated blood platelets have been shown to significantly inhibit plasma fibrinolytic activity before and after venous stasis. This was expressed by a reduction of the digestion area of fibrin dish from 10.3 +/- 3.3 cm2 to 3.7 +/- 1.5 cm2 and from 15.6 +/- 6.8 cm2 to 3.7 +/- 1.7 cm2, respectively.

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