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Effect of diet on exercise tolerance in carnitine palmitoyltransferase II deficiency
Mette C Ørngreen1, Rasmus Ejstrup, John Vissing
1Copenhagen Muscle Research Center and Department of Neurology, National University Hospital, Rigshospitalet, Denmark.
Neurology
|August 27, 2003
Abstract:
It is generally believed that a diet high in carbohydrate improves exercise tolerance in patients with carnitine palmitoyltransferase II (CPT II) deficiency, but it has never been systematically investigated. The authors investigated the effect of a high- vs low-carbohydrate diet on exercise tolerance in four patients with CPT II, who cycled at a constant workload of 50% of VO2max. Exercise tolerance, assessed by exercise duration and perceived exertion, improved on the carbohydrate-rich diet.