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Updated: Jul 13, 2026

Amplifying and Quantifying HIV-1 RNA in HIV Infected Individuals with Viral Loads Below the Limit of Detection by Standard Clinical Assays
Published on: September 26, 2011
Response to systemic HIV viral load suppression correlates with psychomotor speed performance
N Sacktor1, R L Skolasky, P M Tarwater
1Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, USA. sacktor@jhmi.edu
Abstract:
The authors evaluated the association of a virologic response to highly active antiretroviral therapy, or a subsequent rebound, with performance on two measures of psychomotor speed in HIV-positive subjects. Virologic suppression was associated with improved performance on measures of psychomotor speed, and virologic rebound was associated with psychomotor speed performance decline. Changes in plasma HIV viral load in HIV-positive individuals with cognitive slowing correlate with performance on tests of psychomotor speed.

