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Related Experiment Videos

Contrast-enhanced coronary artery imaging using 3D trueFISP.

Vibhas S Deshpande1, Debiao Li

  • 1Department of Radiology, Northwestern University, Chicago, Illinois 60611, USA.

Magnetic Resonance in Medicine
|August 27, 2003
PubMed
Summary
This summary is machine-generated.

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Contrast agents significantly improve blood-myocardial contrast for true fast imaging with steady-state precession (trueFISP) coronary artery imaging, enhancing fat suppression and image quality.

Area of Science:

  • Cardiovascular Magnetic Resonance Imaging
  • Medical Imaging Physics

Background:

  • True fast imaging with steady-state precession (trueFISP) is used for coronary artery imaging.
  • Current fat saturation methods are susceptible to field inhomogeneities, and blood-myocardial contrast is limited by signal transience.

Purpose of the Study:

  • To evaluate T(1)-shortening agents for enhancing blood-myocardial contrast.
  • To develop robust fat suppression for trueFISP coronary artery imaging.

Main Methods:

  • A novel magnetization preparation scheme using saturation and inversion pulses was designed for simultaneous fat and tissue suppression.
  • Computer simulations guided the design, followed by volunteer studies comparing precontrast and contrast-enhanced (CE) imaging.

Main Results:

Related Experiment Videos

  • The new method achieved consistent fat suppression, robust to resonance offsets and insensitive to heart rate variations.
  • Contrast-enhanced imaging demonstrated a 78% increase in blood-myocardial contrast-to-noise ratio (CNR) compared to precontrast imaging.

Conclusions:

  • T(1)-shortening agents are beneficial for improving blood-myocardial contrast in trueFISP coronary artery imaging.
  • The developed magnetization preparation technique enhances fat suppression and overall image quality.