[Charge transfer interaction of atropinum with sigma-electron acceptor and application research]

The charge transfer interaction of vitriol atropinum with iodine in the chloroform was studied. Iodine interacts with atropinum in the chloroform and forms the purple and brown charge transfer complexation. From the ultraviolet spectrum, it is confirmed that the maximum wavelength of the complexation is 280 nm and the apparent molar absorptivities of the complexation is 2.66 x 10(4) L.mol-1.cm-1. Using the equal mole consecutive change method, it is confirmed that the molar combining ratio is 1:1. The reaction mechanism is studied and it is confirmed that the complexation is a kind of supramolecule compound, which is in the syntonic mixed state of non-bonding structure and charge transfer. On the base of the complexation, the method that is used to determine vitriol atropinum injection by the charge transfer spectrophotometry is founded. And the optimal condition of the method was studied. The experiment showed that when the volume ratio of iodine and vitriol atropinum was 2:1, the value of the absorbency of the reaction system was almost stable and the reaction should last out for 20 minutes at room temperature. The method is simple and convenient, short-cut, exclusive. The linear range is 0-35 micrograms.mL-1, the reclaim rate is 99.6%, RSD is 0.83%.