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Mycosis fungoides responding to systemic itraconazole
S M Cooper1, A Sheridan, S Burge
1Department of Dermatology, Oxford Radcliffe Hospitals, Oxford OX3 7LJ, UK. sm_nc@btopenworld.com
Abstract:
Mycosis fungoides is a form of cutaneous lymphoma with a typically indolent course. We describe an unexpected, repeated response to a systemic antifungal agent, itraconazole. The mechanism of action is speculative but itraconazole has marked immunosuppressive activity on T-lymphocyte proliferation in vitro.