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Updated: Sep 20, 2026

A Pipeline to Characterize Structural Heart Defects in the Fetal Mouse
Published on: December 16, 2022
Persistent Truncus Arteriosus
Barbara Ferdman1, Gautam Singh
1Cardinal Glennon Children's Hospital, St. Louis University School of Medicine, Division of Pediatric Cardiology, 1465 S. Grand Boulevard, St. Louis, MO 63104, USA. ferdmanb@slu.edu
Abstract:
Survival of patients with persistent truncus arteriosus, otherwise known as truncus arteriosus communis, has increased over the past several years with advances in congenital heart surgery and postoperative management. Despite the fact that ongoing debate regarding timing for surgical intervention, timing and indication for truncal valve replacement, and the ideal materials to use for the right ventricle to pulmonary artery conduit, perseverance on the part of cardiac surgeons, cardiologists, and the rest of the medical team caring for these patients has resulted in longer and improved quality of life. Early, accurate diagnosis, initial stabilization, and medical management in the perinatal period, and surgical intervention are most important in preventing or decreasing long-term morbidity and mortality.
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