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Therapeutic applications in the chemokine superfamily
Pantea Houshmand1, Albert Zlotnik
1Neurocrine Biosciences, 10555 Science Center Drive, San Diego, CA 92121, USA.
Current Opinion in Chemical Biology
|August 28, 2003
Abstract:
The chemokine superfamily is probably complete. There are 42 human chemokines that through interaction with 18 receptors (which belong to the GPCR superfamily-class A) play pivotal roles in many important human diseases. Here we review some of the most compelling opportunities for drug development in this area.