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3-Diazopyrroles. Part 5 (1). Antibacterial activity of 3-diazo-2-phenylpyrroles
G Cirrincione1, A M Almerico, G Dattolo
1Istituto Farmacochimico, Università, Palermo, Italy.
Farmaco (Societa Chimica Italiana : 1989)
|December 1, 1992
Abstract:
3-Diazo-2-phenylpyrroles 3a-g showed antimicrobial activity against Gram-positive bacteria, whereas against Gram-negative strains the inhibitory activity is limited to derivatives 3a and 3c. The substituents at 4 and 5 positions strongly influence the inhibitory activity, but the presence of the diazo group is crucial for appearance of activity.