Reconfigured colon segments as a ureteral substitute
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Updated: Sep 20, 2026

A Murine Model of Irreversible and Reversible Unilateral Ureteric Obstruction
Published on: December 20, 2014
1Department of Adult and Pediatric Urology, Helios Klinikum Wuppertal, Witten/Herdecke University, Heusnerstrasse 40, 42283 Wuppertal, Germany. b.ubrig@klinikum-wuppertal.de
Abstract:
Reconfigured colon was used as a ureteral substitute in seven selected patients. In four patients, a single reconfigured colon segment was interposed into an extensive defect of the upper ureter. In an additional three patients with solitary kidney, reconfigured colon segments were used for the construction of a conduit. At a mean follow-up of 23 months (range: 2-38 months), no complications related to the reconfigured colon segments were noted. Two patients died of progressive disease, but with no evidence of malfunction of the ureteral substitute. Surgical access is mainly retroperitoneal, and intraperitoneal surgery is minimal. The colonic segments are taken immediately proximal to the ureteral defect, necessitating little mobilization of the mesenteric pedicle. In patients with renal insufficiency or a history of irradiation, this technique may be superior to the use of ileum. Before wider use, long term follow-up data on the uretero-intestinal anastomosis will be necessary.
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