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Updated: Sep 20, 2026

Derivatization of Protein Crystals with I3C using Random Microseed Matrix Screening
Published on: January 16, 2021
A mixed crystal of imperatorin and phellopterin, with C--H...O, C--H...pi and pi-pi interactions
Philip J Cox1, Marcel Jaspars, Yashodharan Kumarasamy
1School of Pharmacy, The Robert Gordon University, Aberdeen, Scotland. p.j.cox@rgu.ac.uk
Abstract:
The crystal structure of 9-(3-methylbut-2-enyloxy)-7H-furo[3,2-g]chromen-7-one-4-methoxy-9-(3-methylbut-2-enyloxy)-7H-furo[3,2-g]chromen-7-one (0.926/0.074), 0.926C(16)H(14)O(4)*- x 0.074C(17)H(16)O(5), is characterized by two independent imperatorin molecules in the asymmetric unit, which exhibit different side-chain conformations. A small amount of phellopterin overlaps with one of the two imperatorin molecules. The supramolecular structure is supported by C--H...O, C--H...pi and pi-pi interactions.
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