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Peripheral parenteral nutrition.

A D G Anderson1, D Palmer, J MacFie

  • 1Combined Gastroenterology Department, Scarborough Hospital, Woodlands Drive, Scarborough YO12 6QL, UK.

The British Journal of Surgery
|August 29, 2003
PubMed
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Effective peripheral parenteral nutrition (PPN) is achievable in approximately 50% of inpatients. This review discusses optimal PPN strategies and practical administration recommendations due to current practice variations.

Area of Science:

  • Clinical Nutrition
  • Parenteral Nutrition Therapy

Background:

  • Peripheral parenteral nutrition (PPN) represents a significant portion of nutrition support in the UK.
  • Lack of consensus guidelines leads to considerable variability in PPN practices.
  • Clinical trial heterogeneity impedes direct comparisons and meta-analyses of PPN.

Purpose of the Study:

  • To review the current evidence and practices surrounding peripheral parenteral nutrition (PPN).
  • To provide practical recommendations for the effective administration of PPN in adult inpatients.

Main Methods:

  • Comprehensive literature search of Medline, Embase, and Cochrane databases for PPN clinical trials.
  • Inclusion of relevant studies from reference lists and author collections.

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Main Results:

  • Peripheral parenteral nutrition (PPN) can be effectively administered to approximately 50% of inpatient population.
  • Evidence regarding optimal feed composition, cannula selection, infusion techniques, and pharmacological interventions is discussed.

Conclusions:

  • Effective PPN is feasible for a substantial subset of inpatients.
  • Discussion includes evidence-based recommendations for optimizing PPN delivery and administration.