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[Visual analysis of EEG in children with a cavum of the septum pellucidum]
Alicja Kubik1, Marek Kaciński, Michaela Pakszys
1Klinika Neurologii Dzieciecej Collegium Medicum Uniwersytetu Jagiellońskiego, Kraków. neupedkr@cm-uj.krakow.pl
Insights
Children with cavum of the spectrum pellucidum (CSP) show altered brain bioelectric activity on EEG, suggesting potential links to neurodevelopmental issues. Further quantitative analysis is recommended for accurate identification.
Area of Science:
- Neuroscience
- Developmental Pediatrics
- Medical Imaging
Background:
- Cavum of the spectrum pellucidum (CSP) is a marker of brain dysgenesis.
- Neuropsychological impairments are suspected in children with CSP.
- Brain hemisphere bioelectric activity may be affected in children with CSP.
Purpose of the Study:
- To investigate differences in electroencephalography (EEG) patterns between children with and without CSP.
- To explore the relationship between CSP and brain bioelectric activity.
Main Methods:
- Visual analysis of 40-minute EEG recordings from 41 children with CSP and 32 controls.
- EEG data were analyzed by two licensed electroencephalography physicians.
- Utilized a 16-channel MedtronicDantec EEG system.
Main Results:
- Children with CSP exhibited significantly more immature and irregular basic EEG activity.
- Increased frequency and amplitude asymmetry, slow activity, and abnormal graphoelements were observed in children with CSP.
- Significant differences in EEG patterns were noted between the CSP and control groups.
Conclusions:
- Visual EEG analysis reveals significant differences in children with CSP.
- Quantitative EEG analysis methods are necessary for precise identification of EEG patterns in patients with CSP.
Hypothesis:
It is possible that bioelectric activity of the both brain hemispheres is changed in children with a cavum of the spectrum pellucidum (CSP), a marker of brain dysgenesis. It could be connected probably with neuropsychological impairment in children with CSP.
Material:
Visual analysis of EEG was done in 41 children with CSP aged 2 months to 17 years and in 32 children without CSP aged 3 months to 17 years. It induced 8 EEG curve pairs from each child, that means 328 pairs in CSP and 256 pairs without CSP children.
Methods:
EEG pattern was analysed by two physicians with an electro-encephalography license and data are a mean value of both analysis. Analysed were 40 minute EEG patterns, registered by 16 channels MedtronicDantec EEG PL-270 Video Option Aparat.
Results:
Brain bioelectric activity was significantly more often immature and basic activity irregular in children with CSP than in the group without CSP. Asymmetry of frequency and amplitude and slow activity were also significantly more often observed in children with CSP. Abnormal graphoelements were also significantly more often disclosed in children with CSP.
Conclusions:
Visual analysis disclosed significant differences of EEG pattern in children with and without CSP. For identification of EEG from patient with CSP the quantitative method of analysis is necessary.
