Related Experiment Video
Updated: Sep 20, 2026

Rat Hindlimb Below-Knee Amputation Model and Immediate Targeted Muscle Reinnervation
Published on: May 22, 2026
[Prevention of lower limb necrosis and amputation by femoro-crural bypass: indications, techniques and results]
H Van Damme1, E Baguet, L Zhang
1Service de Chirurgie cardio-vasculaire, CHU, Sart Tilman, Liège. hvandamme@chu.ulg.ac.be
Insights
Vascular surgeons can now minimize limb amputations for chronic critical limb ischemia patients. Advances in revascularization, including distal bypass surgery, offer new hope for limb salvage.
Area of Science:
- Vascular Surgery
- Endovascular Procedures
- Diabetic Arteriopathy
Context:
- Chronic critical limb ischemia (CLI) presents significant challenges in vascular surgery.
- Minimizing primary amputation rates is a key goal in CLI management.
- Diabetic arteriopathy is a prevalent cause of CLI, necessitating specialized treatment approaches.
Purpose:
- To review the prevalence and causes of CLI, focusing on diabetic arteriopathy.
- To describe crural and pedal vessel revascularization techniques, including innovative distal bypass methods.
- To analyze published series and the authors' decade-long experience with infrapopliteal bypass surgery.
Summary:
- This study discusses chronic critical limb ischemia (CLI), its prevalence, and causes, with emphasis on diabetic arteriopathy.
- It details crural and pedal vessel revascularization techniques and introduces an innovative tourniquet method for distal bypass surgery.
- A review of existing literature and the authors' extensive experience in bypass surgery for CLI is presented.
Impact:
- Improved understanding of CLI management strategies, particularly for diabetic patients.
- Highlights the efficacy of advanced revascularization techniques in limb salvage.
- Provides valuable insights for vascular surgeons managing complex lower extremity ischemia.
Abstract:
Limb threatening ischemia is a challenge for the vascular surgeon. Recent progress in revascularization procedures allow to minimize the primary amputation rate in the management of chronic critical limb ischemia. The authors discuss the prevalence and causes of chronic critical limb ischemia, with a special interest for diabetic arteriopathy. The technique of crural and pedal vessel revascularization is described, as well as the innovative tourniquet technique for distal bypass surgery. A review of published series of infrapopliteal bypass surgery is made. The experience of the authors during last decade with crural and pedal bypass surgery is analyzed.
Related Concept Videos
Peripheral Artery Disease V: Postoperative Nursing Management
Peripheral Artery Disease III: Interprofessional Care