[Quantitative analysis of rutin and vitamin C by NIR FTIR]

In this paper, near-infrared diffuse reflectance spectroscopy(NIRDRS) method was used as a quantitative tool to measure the solid mixture of rutin and vitamin C by collecting NIR spectra in the range 7,000-3,900 cm-1. The quantitative mathematics model was established with partial least squares(PLS) method. The correlation coefficient was 99.75%, the standard error of Rutin was 0.363%, and the standard error of Vitamin C was 1.078%. The methods are rapid, exact and nondestructive to samples. The components of the samples can be individually analyzed with high accuracy and precision, so NIRDRS can be a useful method of quality control of pharmaceuticals in the future.