NMR-based screening technologies
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Updated: Sep 20, 2026

NMR-Based Fragment Screening in a Minimum Sample but Maximum Automation Mode
Published on: June 4, 2021
Murray Coles1, Markus Heller, Horst Kessler
1Institut für Organische Chemie und Biochemie, Technische Universität München Lichtenbergstrasse 4, 85747, Garching, Germany.
Abstract:
NMR-based ligand screening is now an established field in its own right. In recent years, advances in both methodology and hardware have broadened its range of applications and pushed back practical limitations, leading to the growing importance of NMR screening as a tool in industrial drug research. An overview of new screening methods and applications is presented here, and ways in which NMR-screening is being used in cooperation with other screening techniques are discussed.
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