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Updated: Sep 20, 2026

Establishment of a Segmental Femoral Critical-size Defect Model in Mice Stabilized by Plate Osteosynthesis
Published on: October 12, 2016
Can monocortical miniplates provide bony compression?. An experimental model
C J Kerawala1, W Allan, E D Williams
1Department of Oral and Maxillofacial Surgery, North Hampshire Hospital, Aldermaston Road, Basingstoke, Hampshire RG24 9NA, UK. c.kerawala@cwcom.net
Abstract:
Some maxillofacial surgeons advocate that screws in monocortical plate systems be placed eccentrically in an attempt to provide compression between bony ends. We sought to quantify the degree of displacement and compressive forces made possible by such eccentric placement in an experimental model using five miniplates and Perspex blocks to simulate mandibular fractures. The maximum displacement obtained was 0.67 mm and the maximal compressive force 5.2N (SEM=0.9, range=2.7-7.1). This demonstrates that eccentric placement of screws can achieve some compression and displacement at the fracture interface and that the forces obtained are close to those predictable from the dimensions of the burr, screw, and miniplate.
