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Antibacterial activity of Pterocarpus indicus
1Department of Applied Sciences, Papua New Guinea University of Technology, PMB, Lae, Papua New Guinea. rkhan@dg.com.pg
Fitoterapia
|August 30, 2003
Summary
Pterocarpus indicus plant parts showed broad antibacterial activity, particularly in butanol and methanol extracts. However, no antifungal effects were observed against molds.
Area of Science:
- Pharmacognosy
- Phytochemistry
- Microbiology
Background:
- Pterocarpus indicus, a medicinal plant, has traditional uses suggesting therapeutic properties.
- Investigating the phytochemical constituents and biological activities of Pterocarpus indicus is crucial for potential drug development.
Purpose of the Study:
- To evaluate the antibacterial and antifungal activities of various Pterocarpus indicus plant fractions.
- To identify potent fractions for further investigation in antimicrobial drug discovery.
Main Methods:
- Successive partitioning of Pterocarpus indicus leaves, root, and stem bark using solvents: petrol, dichloromethane, ethyl acetate, butanol, and methanol.
- In vitro screening of all obtained fractions for antibacterial activity against a spectrum of bacteria.
- In vitro screening of all obtained fractions for antifungal activity against selected molds.
Main Results:
- All tested fractions demonstrated a wide range of antibacterial activity.
- The butanol and methanol fractions exhibited the most significant antibacterial effects.
- None of the fractions displayed any activity against the tested molds.
Conclusions:
- Pterocarpus indicus possesses significant antibacterial properties, with butanol and methanol fractions being particularly effective.
- The plant's extracts are not effective against fungal infections caused by molds.
- Further research into the active compounds within the butanol and methanol fractions could lead to novel antibacterial agents.