Evaluation of diagnosis of ovarian malignancy using immunohistochemical technique

Immunohistochemical staining was performed on biopsy specimens from normal ovary and also from abnormal ovarian growth using monoclonal OKT9 antibody. The results showed positive reaction in 8.77% of normal ovarian specimens removed during laparotomy. The reaction was also positive in 15.7% in cases diagnosed by histological examination as benign ovarian growth. Specimens proved by histological examination to be malignant showed reaction with OKT9 in 100%. The significance of this finding is discussed.