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Related Experiment Videos

[Contrast media in hepatic MRI].

J Grellet1, M F Bellin, E Dion

  • 1Service de Radiologie Centrale, Hôpital La Pitié, Paris.

Journal De Radiologie
|October 1, 1992
PubMed
Summary

This review covers current and investigational magnetic resonance (MR) contrast agents, including gadolinium chelates and emerging iron oxide and manganese compounds. It details agents in human trials and those in animal studies for enhanced medical imaging.

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Area of Science:

  • Radiology
  • Medical Imaging
  • Biomedical Engineering

Context:

  • Magnetic Resonance (MR) imaging relies on contrast media to enhance image quality and diagnostic accuracy.
  • Current MR contrast agents primarily utilize gadolinium chelates.
  • There is ongoing research into novel contrast agents to improve safety and efficacy.

Purpose:

  • To review currently available commercial MR contrast media (gadolinium chelates).
  • To survey emerging contrast agents under investigation.
  • To discuss agents in human trials and preclinical animal studies.

Summary:

  • The article examines established gadolinium chelate contrast agents.
  • It explores novel agents like super-magnetic iron oxides and manganese compounds in human trials.
  • Additionally, it covers agents in animal studies, including ferric chelates, liposomal gadolinium, and gadolinium-albumin compounds.

Impact:

  • Provides a comprehensive overview of the MR contrast media landscape.
  • Highlights potential future advancements in contrast agent technology.
  • Informs researchers and clinicians about the pipeline of new diagnostic tools.

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