Iliac artery stenting in patients with poor distal runoff: Influence of concomitant infrainguinal arterial
Carlos H Timaran1, Takao Ohki, Nicholas J Gargiulo
1Department of Surgery, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, New York 10467, USA. timaran1@msn.com
Insights
Concomitant infrainguinal arterial reconstruction (CIAR) does not improve iliac artery stent patency in patients with poor distal runoff. These infrainguinal bypass procedures should be reserved for patients with limb-threatening ischemia.
Area of Science:
- Vascular Surgery
- Interventional Cardiology
- Peripheral Artery Disease
Background:
- Inadequate infrainguinal runoff is a known risk factor for iliac stent failure.
- The impact of concomitant infrainguinal arterial reconstruction (CIAR) on iliac stent patency remains unclear.
Purpose of the Study:
- To evaluate the influence of CIAR on the outcomes of iliac angioplasty and stenting (IAS) in patients with poor distal runoff.
- To determine if combining IAS with CIAR improves iliac stent patency compared to IAS alone.
Main Methods:
- A retrospective study of 68 IAS procedures (78 stents) in 62 patients with poor distal runoff (runoff score >=5) between 1996 and 2001.
- Outcomes were analyzed using Kaplan-Meier and Cox proportional hazards models, adhering to SVS/AAVS reporting standards.
- Patients were divided into two groups: IAS with CIAR (n=31) and IAS alone (n=37).
Main Results:
- Patients undergoing IAS with CIAR had more extensive iliac artery disease (TASC type C lesions) and were older.
- Primary iliac stent patency rates at 1, 3, and 5 years were not significantly different between the IAS with CIAR group (87%, 54%, 42%) and the IAS alone group (76%, 66%, 55%).
- Performing CIAR did not impact primary iliac stent patency (RR 1.1, P=.81), but there was a trend towards improved limb salvage in the IAS with CIAR group (P=.07).
Conclusions:
- In patients undergoing IAS for poor distal runoff, CIAR does not enhance iliac artery stent patency.
- Infrainguinal bypass procedures should be considered for patients not improving clinically or those with limb-threatening ischemia.
- The decision to perform CIAR should be based on clinical indication rather than solely on improving iliac stent patency.
Objective:
Inadequate infrainguinal runoff is considered an important risk factor for iliac stent failure. However, the influence of concomitant infrainguinal arterial reconstruction (CIAR) on iliac stent patency is unknown. This study evaluated the influence of CIAR on outcome of iliac angioplasty and stenting (IAS) in patients with poor distal runoff.
Methods:
Over 5 years (1996 to 2001), 68 IAS procedures (78 stents) were performed in 62 patients with poor distal runoff (angiographic runoff score >or=5). The SVS/AAVS reporting standards were followed to define outcome variables and risk factors. Data were analyzed with both univariate analysis (Kaplan-Meier method [K-M]) and regression analysis (Cox proportional hazards model).
Results:
Indications for iliac artery stenting were disabling claudication (59%) and limb salvage (41%). Of the 68 procedures, IAS with CIAR was performed in 31 patients (46%), and IAS alone was performed in 37 patients (54%). Patients undergoing IAS with CIAR were older (P =.03) and had more extensive and multifocal iliac artery occlusive disease, with more TASC (TransAtlantic Inter-Society Consensus) type C lesions (P =.03), compared with patients undergoing IAS alone. No other significant differences in risk factors were noted. Runoff scores between patients undergoing IAS with CIAR and those undergoing IAS alone were not significantly different (median runoff scores, 6 [range, 5-8] and 7 [range, 5-9], respectively; P =.77). Primary stent patency rate at 1, 3, and 5 years was 87%, 54%, and 42%, respectively, for patients undergoing IAS with CIAR, and was 76%, 66%, and 55%, respectively, for patients undergoing IAS. Univariate analysis revealed that primary stent patency rate was not significantly different between the 2 groups (K-M, log-rank test, P =.81). Primary graft patency rate for CIAR was 81%, 52%, and 46% at 1, 3, and 5 years, respectively. Performing CIAR did not affect primary iliac stent patency (relative risk, 1.1; 95% confidence interval, 0.49-2.47; P =.81). Overall, there was a trend toward improved limb salvage in patients undergoing IAS with CIAR, compared with those undergoing IAS alone (K-M, log rank test, P =.07).
Conclusion:
In patients undergoing IAS with poor distal runoff, CIAR does not improve iliac artery stent patency. Infrainguinal bypass procedures should therefore be reserved for patients who do not demonstrate clinical improvement and possibly for those with limb-threatening ischemia.
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