Therapeutic procedures of sublingual immunotherapy in clinical practice

Clinical practice shows that a number of important measures are required to reach a high efficacy of sublingual immunotherapy. These measures include a specific and exact diagnosis of allergy, a high and reliable compliance of the patient, detailed guidance and explanation by the physician, and a strict monitoring of clinical symptoms and possible side effects. The complex inflammatory situation of the allergic patient, especially concerning the conjunctival, nasal and bronchial mucosa as well as eczema, should be explored in detail and treated with anti-inflammatory medication. After having reviewed the international literature combined with personal practical experience, we interpret and suggest that noninflammatory circumstances increase the chances of success of immunotherapies in allergy; nonetheless, several of these interpretations have not yet been confirmed by clinical studies.