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[The characteristics of cardiomyopathy in different geographical regions]
Insights
Hypertrophic cardiomyopathy (HC) in Dubai presents silently, affecting the basal septum and right ventricle. Dilated cardiomyopathy (DC) in Dubai shows weaker cardiac insufficiency and arrhythmia compared to Moscow.
Area of Science:
- Cardiology
- Cardiovascular Diseases
- Clinical Research
Background:
- Cardiomyopathies, including hypertrophic cardiomyopathy (HC) and dilated cardiomyopathy (DC), represent significant global health concerns.
- Understanding region-specific variations in disease presentation and etiology is crucial for targeted clinical management and public health strategies.
Purpose of the Study:
- To compare the region-specific characteristics of hypertrophic cardiomyopathy (HC) and dilated cardiomyopathy (DC) in patients from Dubai, UAE, and Moscow, Russia.
- To identify distinct clinical presentations, etiological factors, and affected cardiac regions for HC and DC in these two distinct populations.
Main Methods:
- A comparative study involving 108 patients diagnosed with HC or DC.
- Data collection included patient demographics, clinical presentation, echocardiographic findings, and etiological factors.
- Patients were recruited from Dubai (n=49) and Moscow (n=59).
Main Results:
- Hypertrophic cardiomyopathy (HC) in Dubai exhibited a predominantly silent, latent course, with primary involvement of the basal septum and right ventricle.
- Moscow patients with HC showed a higher prevalence of apical lesions and more severe myocardial impairment.
- Dilated cardiomyopathy (DC) in Dubai was associated with reduced cardiac insufficiency and arrhythmia.
- Idiopathic and periportal DC were more frequently observed in Dubai, whereas alcohol and viral infections were more common etiologies for DC in Moscow.
Conclusions:
- Significant regional differences exist in the clinical presentation and etiology of hypertrophic cardiomyopathy (HC) and dilated cardiomyopathy (DC) between Dubai and Moscow.
- These findings highlight the importance of considering geographical and environmental factors in the diagnosis and management of cardiomyopathies.
Abstract:
Region-specific characteristics of hypertrophic cardiomyopathy (HC) and dilated cardiomyopathy (DC) were compared for 108 relevant patients living in Dubai (United Arab Emirates) and Moscow (Russia). Out of 49 citizens of Dubai 17 had HC, 32 DC, and 59 Moscow patients had HC in 23, DC in 36 cases. It was found that HC in Dubai tends to run a silent latent course, involving mainly basal septum and right ventricle. Apical lesions were more typical for Moscow citizens who also display more severe myocardial impairment. DC in Dubai produces weaker cardiac insufficiency and arrhythmia. Incidence of idiopathic and periportal DC proved higher in Dubai, while alcohol and virus infection underlie DC more frequently in Moscow.