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[Fentanyl prevents the pain at the site of propofol injection]

D Chessa1, F Cossu, G Serra

  • 1Servizio di Anestesiologia e Rianimazione, Ospedale Pediatrico F.lli Crobu, Iglesias, Cagliari.

Minerva Anestesiologica
|December 1, 1992
PubMed

Insights

Fentanyl effectively reduces pain from propofol injection in children undergoing surgery. This study shows fentanyl administration is a valid method for alleviating injection site discomfort.

Area of Science:

  • Anesthesiology
  • Pediatric Surgery
  • Pain Management

Background:

  • Propofol injection can cause pain, leading to patient distress.
  • Pain on injection is a common issue with intravenous anesthetics like propofol.
  • Effective pain management strategies are crucial in pediatric anesthesia.

Purpose of the Study:

  • To evaluate the efficacy of fentanyl in mitigating pain associated with propofol injection.
  • To compare pain reduction using fentanyl versus a placebo (saline).
  • To determine if pre-administration of fentanyl is a viable method for pain relief during propofol induction.

Main Methods:

  • A randomized controlled trial involving 28 children undergoing elective surgery.
  • Fentanyl (2 micrograms/kg) was administered intravenously immediately before propofol.
  • A control group received intravenous saline before propofol administration.

Main Results:

  • Children receiving fentanyl experienced significantly less pain at the propofol injection site compared to the control group.
  • The reduction in pain was statistically significant.
  • Fentanyl demonstrated a clear benefit in reducing injection site pain.

Conclusions:

  • Pre-administration of fentanyl is an effective strategy for reducing pain during propofol injection in pediatric patients.
  • Fentanyl offers a valid procedural approach to manage injection pain associated with propofol.
  • This finding supports the use of fentanyl as part of anesthetic protocols to improve patient comfort.

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