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[Post-anesthesia rhabdomyolysis syndrome following muscular stress. 2 case reports]
P Grosso1, P L Petrini, R Massei
1Regione Lombardia, USSL n. 1, Servizio di Anestesia e Rianimazione, Ospedale Civile Castel San Giovanni, Piacenza.
Abstract:
Effort rhabdomyolysis is a syndrome which takes the form of a pathology with different etiopathogenetic stages. General anesthesia may trigger off acute muscular cytolysis which is probably influenced by the inflammatory surgical pathology itself. The observation of two cases of post-anesthetic rhabdomyolysis following muscular stress suggest that the exhaustion of muscle energy reserves and the consequent alteration of the ATP/ADP ratio may act as a trigger mechanism for this syndrome. Its close relationship with malignant hyperthermia makes a precise anamnesis vitally important, especially in relation to recent intense physical effort in patients undergoing emergency surgery for acute pathologies.