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Development and Validation of an Ultrasensitive Single Molecule Array Digital Enzyme-linked Immunosorbent Assay for Human Interferon-α
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Published on: June 14, 2018

Ultralow doses of anti-idiotypic antibodies to human gamma-interferon: immunotropic properties

E Yu Sherstoboev1, N M Masnaya, A A Churin

  • 1Institute of Pharmacology, Tomsk Research Center, Siberian Division of the Russian Academy of Medical Sciences, Tomsk.

Bulletin of Experimental Biology and Medicine
|September 2, 2003
PubMed

We studied the effects of ultralow doses of anti-idiotypic antibodies to human gamma-interferon on humoral immune response in experimental animals immunized with a thymus-dependent antigen, delayed-type hypersensitivity, and phagocytic activity of neutrophils in the peritoneal exudate. This preparation stimulated the humoral immune response and activated phagocytosis, but had no effect on functional activity of T cells.

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