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Related Concept Videos

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Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
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Positron Emission Tomography (PET) is a medical imaging technique that provides crucial insights into the body's physiological functions at a molecular level. It is an indispensable resource for diagnosing, staging, and monitoring various illnesses, notably cancer, neurological disorders, and cardiovascular conditions.
Fundamental Principles of PET
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Imaging Studies III: Gastrointestinal Motility Studies and Virtual Colonoscopy01:26

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This lesson explores three gastrointestinal imaging techniques: radionuclide testing, colonic transit studies, and virtual colonoscopy.
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Imaging Studies for Cardiovascular System V: CT01:28

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Cardiac computed tomography (CT) scanning is an advanced cardiac imaging technique that utilizes CT technology, with or without intravenous (IV) contrast, to produce accurate cross-sectional virtual slices of specific areas of the heart, coronary circulation, and major blood vessels such as the aorta, pulmonary veins, and arteries. The computer processes these slices to generate three-dimensional images. Multidetector CT (MDCT) is a rapid form of CT scanning that captures multiple slices...
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Imaging Studies III: Computed Tomography01:27

Imaging Studies III: Computed Tomography

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DefinitionComputed Tomography (CT) of the genitourinary (GU) tract is a non-invasive imaging modality that utilizes X-rays and computer processing to generate detailed cross-sectional images of the urinary system, encompassing the kidneys, ureters, bladder, and adjacent structures such as the adrenal glands.PurposeCT scans of the GU tract serve several diagnostic and therapeutic purposes, including:Diagnosis of Urinary Tract Diseases: Detects kidney stones, tumors, cysts, and congenital...
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Imaging Studies VI: Voiding Cystourethrography and Cystography01:22

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Voiding Cystourethrography (VCUG) and Cystography are specialized radiographic procedures used to examine the structure and function of the bladder and urethra.Voiding Cystourethrography (VCUG)A Voiding Cystourethrogram (VCUG) is a diagnostic imaging procedure that assesses the anatomy and function of the lower urinary tract. It focuses on the bladder, bladder neck, and urethra, helping detect abnormalities such as vesicoureteral reflux (VUR)—the backward or reverse flow of urine into the...
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Computerized tomographic colonography: performance evaluation in a retrospective multicenter setting.

C Daniel Johnson1, Alicia Y Toledano, Benjamin A Herman

  • 1Department of Radiology, Mayo Clinic, Rochester, Minnesota 55905, USA.

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|September 2, 2003
PubMed
Summary
This summary is machine-generated.

Computerized tomographic colonography accurately detects large colorectal polyps. This multicenter study found its performance comparable to other screening methods, supporting its use in colorectal cancer detection.

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Area of Science:

  • Gastroenterology
  • Radiology
  • Medical Imaging

Background:

  • No prior multicenter studies evaluated computerized tomographic colonography (CTC) performance and interobserver variability.
  • Assessing CTC accuracy for detecting significant colorectal neoplasia is crucial.

Purpose of the Study:

  • To evaluate the accuracy of CTC in detecting clinically important colorectal neoplasia (polyps ≥10 mm) across multiple institutions.
  • To assess interobserver variability in CTC interpretation.

Main Methods:

  • Retrospective analysis of 93 patients from 8 medical centers who underwent both CTC and colonoscopy.
  • Eighteen radiologists interpreted CTC using different software platforms, blinded to colonoscopy and pathology results.
  • Colonoscopy and pathology reports served as the reference standard.

Main Results:

  • The average area under the ROC curve for detecting lesions ≥10 mm was 0.80.
  • Average sensitivity and specificity for detecting patients with lesions ≥10 mm were 75% and 73%, respectively.
  • Per-polyp sensitivity was 75%; no significant difference in performance was noted across software platforms.

Conclusions:

  • Computerized tomographic colonography demonstrates favorable performance compared to fecal occult blood testing, flexible sigmoidoscopy, and barium enema.
  • Further prospective studies are warranted to evaluate CTC in a screening population.
  • Observer experience may influence CTC performance.