Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Bilateral MRI-guided stereotactic cingulotomy for intractable pain.

P K Pillay¹, S J Hassenbusch

¹Department of Neurosurgery, Cleveland Clinic Foundation, Ohio.

Stereotactic and Functional Neurosurgery

|January 1, 1992

Summary

Bilateral radiofrequency cingulotomy offered significant pain relief for patients with intractable cancer pain. This minimally invasive procedure showed promising results for managing severe, chronic pain conditions.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Development of clonidine hydrochloride injections for epidural intrathecal administration.

International journal of pharmaceutical compounding·2013

Same author

Cost effectiveness of intrathecal therapy for pain.

Neuromodulation : journal of the International Neuromodulation Society·2011

Same author

Alternative intrathecal agents for the treatment of pain.

Neuromodulation : journal of the International Neuromodulation Society·2011

Same author

Future trends in the development of local drug delivery systems: intraspinal, intracerebral, and intraparenchymal therapies.

Neuromodulation : journal of the International Neuromodulation Society·2011

Same author

Preclinical toxicity study of intrathecal administration of the pain relievers dextrorphan, dextromethorphan, and memantine in the sheep model.

Neuromodulation : journal of the International Neuromodulation Society·2011

Same author

A method for training physicians to implant intrathecal catheters.

Neuromodulation : journal of the International Neuromodulation Society·2011

Area of Science:

Neurosurgery
Pain Management
Interventional Radiology

Background:

Intractable cancer and noncancer pain pose significant challenges.
Radiofrequency ablation is an established technique for pain management.

Purpose of the Study:

To evaluate the efficacy of bilateral radiofrequency cingulotomy for intractable pain.
To assess pain relief in patients with cancer and noncancer pain.

Main Methods:

Bilateral radiofrequency cingulotomy performed in 10 patients.
Stereotactic guidance using magnetic resonance imaging (MRI) and local anesthesia.
Radiofrequency lesion placement at 75 degrees for 60 seconds.

Main Results:

8 patients with metastatic cancer pain experienced variable relief: 4 excellent, 1 fair, 2 poor.

Related Experiment Videos

2 patients with benign conditions (neurofibromatosis, thalamic stroke pain) had mixed outcomes: 1 excellent, 1 poor.

Long-term follow-up (1 year) showed sustained relief in some cases.

Conclusions:

Bilateral radiofrequency cingulotomy is a viable option for intractable pain.
The procedure demonstrated potential for managing complex pain syndromes.
Further research is warranted to optimize patient selection and outcomes.