Related Experiment Video
Updated: Sep 20, 2026

Functionalized Spirocyclic Heterocycle Synthesis and Cytotoxicity Assay
Published on: February 9, 2021
Synthesis and cytotoxic activity of A-ring modified betulinic acid derivatives
Young-Jae You1, Yong Kim, Nguyen-Hai Nam
1College of Pharmacy, Chungnam National University, Taejon 305-764, South Korea.
Abstract:
New A-ring modified betulinic acid derivatives having small steric hindrance were prepared and tested for cytotoxic activity on 3 cancer cell lines: 10 compounds showed stronger cytotoxic activity than betulinic acid. Especially, the compounds bearing 1-ene-3-oxo with electron-withdrawing groups at C2 showed strong cytotoxicity.
More Related Videos
06:34Synthesis of Antiviral Tetrahydrocarbazole Derivatives by Photochemical and Acid-catalyzed C-H Functionalization via Intermediate Peroxides (CHIPS)
Published on: June 20, 2014
13:17In Vitro and In Vivo Evaluation of Photocontrolled Biologically Active Compounds - Potential Drug Candidates for Cancer Photopharmacology
Published on: September 29, 2023
Related Concept Videos
Antifungal Agents
Inhibitors of Bacterial DNA Synthesis
ortho–para-Directing Activators: –CH3, –OH, –⁠NH2, –OCH3
Directing and Steric Effects in Disubstituted Benzene Derivatives