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Published on: July 17, 2009
Primordial germ-cell development: the zebrafish perspective
1Germ Cell Development, Max-Planck-Institute for Biophysical Chemistry, Am Fassberg 11, 37070 Goettingen, Germany. eraz@gwdg.de
Nature Reviews. Genetics
|September 3, 2003
Abstract:
Primordial germ cells follow a characteristic developmental path that is manifested in the specialized regulation of basic cell functions and behaviour. Recent studies in zebrafish have greatly enhanced our understanding of the mode of specification of primordial germ cells, cell-fate maintenance and the migration of these cells towards their target, the gonad, where they differentiate into gametes.
